InterPAD - DETAILS

Docosahexaenoic acid, Doconexent, Cervonic acid, 6217-54-5, cis-4,7,10,13,16,19-Docosahexaenoic acid, Docosahexaenoate, Doconexentum, Doconexento, Doxonexent, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, all-cis-DHA, AquaGrow Advantage, Martek DHA HM, Ropufa 60, Monolife 50, all-Z-Docosahexaenoic acid, Doconexent [INN], CCRIS 7670, UNII-ZAD9OKH9JC, ZAD9OKH9JC, all-cis-4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid, Algal DHA, Docosaheaenoic-acid, Docosahexaenoic acid (all-Z), all-cis-docosa-4,7,10,13,16,19-hexaenoic acid, DTXSID5040465, (all-Z)-4,7,10,13,16,19-Docosahexaenoic acid, CHEBI:28125, DOCOSAHEXANOIC ACID, Doconexentum [INN-Latin], Doconexento [INN-Spanish], FA 22:6, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid, 4,7,10,13,16,19-Docosahexaenoic acid, (all-Z)-, C22:6 (n-3), CHEMBL367149, 22:6 n-3, docosahexaenoic acid(DHA), Retriacyl (proposed trade name), delta4,7,10,13,16,19-Docosahexaenoic acid, 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, Docosahexaenoic acid (c22:6 n3), OMEGA-3 MARINE TRIGLYCERIDES, MFCD00065722, efalex, NCGC00161345-04, DOCOSAHEXAENOIC ACID (22:6 n-3), 22:6(n-3), Doconexentum (INN-Latin), cis-4,7,10,13,16,19-Docosahexanoic acid, Doconexento (INN-Spanish), A320050000, C22:6n-3,6,9,12,15,18, Marinol D 50TG, 4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-, SR-05000002130, Cervonate, 1fdq, Docohexanenoic Acid, Complete Natal DHA, Docosahexanenoic acid, all-Z-Docosahexaenoate, WesNatal DHA Complete, Spectrum5_002062, OBTREX DHA Combo Pack, Obstetrix DHA Combo Pack, Docosahexaenoic acid (6CI), SCHEMBL19577, BSPBio_001298, MLS004773950, BML3-B02, GTPL1051, DTXCID3020465, BCBcMAP01_000145, CHEBI:36005, DOCOSAHEXAENOIC ACID [MI], DTXSID401018161, HMS1361A20, HMS1791A20, HMS1989A20, HMS3402A20, HMS3649J15, HXA, HY-B2167, DOCOSAHEXAENOIC ACID [VANDF], Tox21_111992, BDBM50210259, DOCOSAHEXAENOIC ACID [MART.], LMFA01030185, DOCOSAHEXAENOIC ACID [USP-RS], DOCOSAHEXAENOIC ACID [WHO-DD], AKOS015962159, AC-1010, CCG-207958, CCG-208135, CS-6261, DB03756, KL-0761, IDI1_033768, 4,7,10,13,16,19-Docosahexaenoate, NCGC00161345-01, NCGC00161345-02, NCGC00161345-03, NCGC00161345-05, NCGC00161345-07, all cis- Docosahexaenoic acid (cis-DHA), BP-29833, SMR001881493, CAS-6217-54-5, cis-4,7,10,13,16,19-Docosahexanoate, D2226, FT-0623913, S6454, C06429, H10987, AB01563379_01, DOCOSAHEXAENOIC ACID (DHA) (C22:6 N3), Select-OB Plus DHAPrenatal Supplement Plus DHA, Vitafol-OB Plus DHAPrenatal Supplement Plus DHA, Q423345, DHA-[21,21,22,22,22-d5], SR-05000002130-1, SR-05000002130-4, BRD-K39965020-001-02-6, 4,7,10,13,16,19-Docosahexaenoic acid, (all cis)-, cis-4,7,10,13,16,19-Docosahexaenoic acid, >=98%, FA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)), z,z,z,z,z,z-docosa-4,7,10,13,16,19-hexaenoic acid, 800E8E72-BBF4-46F7-A60B-B8F2B54669C7, C22H32O2 (cis-4,7,10,13,16,19-docosahexaenoic acid), 4,7,10,13,16,19-Docosahexaenoic acid, (all-Z)- (8CI), cis-4,7,10,13,16,19-Docosahexaenoic acid, analytical standard, Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3), (4Z,7Z,10Z,13Z,16Z, 19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4, 7,10,13,16,19-hexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19- hexaenoic acid, 4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)- (9CI), 1024594-51-1, cis-4,7,10,13,16,19-Docosahexaenoic acid, 500 mug/mL in ethanol, certified reference material

Name	Docosahexaenoic acid
PubChem CID	445580
Molecular Weight	328.5g/mol
Synonyms	Docosahexaenoic acid, Doconexent, Cervonic acid, 6217-54-5, cis-4,7,10,13,16,19-Docosahexaenoic acid, Docosahexaenoate, Doconexentum, Doconexento, Doxonexent, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, all-cis-DHA, AquaGrow Advantage, Martek DHA HM, Ropufa 60, Monolife 50, all-Z-Docosahexaenoic acid, Doconexent [INN], CCRIS 7670, UNII-ZAD9OKH9JC, ZAD9OKH9JC, all-cis-4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid, Algal DHA, Docosaheaenoic-acid, Docosahexaenoic acid (all-Z), all-cis-docosa-4,7,10,13,16,19-hexaenoic acid, DTXSID5040465, (all-Z)-4,7,10,13,16,19-Docosahexaenoic acid, CHEBI:28125, DOCOSAHEXANOIC ACID, Doconexentum [INN-Latin], Doconexento [INN-Spanish], FA 22:6, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid, 4,7,10,13,16,19-Docosahexaenoic acid, (all-Z)-, C22:6 (n-3), CHEMBL367149, 22:6 n-3, docosahexaenoic acid(DHA), Retriacyl (proposed trade name), delta4,7,10,13,16,19-Docosahexaenoic acid, 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, Docosahexaenoic acid (c22:6 n3), OMEGA-3 MARINE TRIGLYCERIDES, MFCD00065722, efalex, NCGC00161345-04, DOCOSAHEXAENOIC ACID (22:6 n-3), 22:6(n-3), Doconexentum (INN-Latin), cis-4,7,10,13,16,19-Docosahexanoic acid, Doconexento (INN-Spanish), A320050000, C22:6n-3,6,9,12,15,18, Marinol D 50TG, 4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-, SR-05000002130, Cervonate, 1fdq, Docohexanenoic Acid, Complete Natal DHA, Docosahexanenoic acid, all-Z-Docosahexaenoate, WesNatal DHA Complete, Spectrum5_002062, OBTREX DHA Combo Pack, Obstetrix DHA Combo Pack, Docosahexaenoic acid (6CI), SCHEMBL19577, BSPBio_001298, MLS004773950, BML3-B02, GTPL1051, DTXCID3020465, BCBcMAP01_000145, CHEBI:36005, DOCOSAHEXAENOIC ACID [MI], DTXSID401018161, HMS1361A20, HMS1791A20, HMS1989A20, HMS3402A20, HMS3649J15, HXA, HY-B2167, DOCOSAHEXAENOIC ACID [VANDF], Tox21_111992, BDBM50210259, DOCOSAHEXAENOIC ACID [MART.], LMFA01030185, DOCOSAHEXAENOIC ACID [USP-RS], DOCOSAHEXAENOIC ACID [WHO-DD], AKOS015962159, AC-1010, CCG-207958, CCG-208135, CS-6261, DB03756, KL-0761, IDI1_033768, 4,7,10,13,16,19-Docosahexaenoate, NCGC00161345-01, NCGC00161345-02, NCGC00161345-03, NCGC00161345-05, NCGC00161345-07, all cis- Docosahexaenoic acid (cis-DHA), BP-29833, SMR001881493, CAS-6217-54-5, cis-4,7,10,13,16,19-Docosahexanoate, D2226, FT-0623913, S6454, C06429, H10987, AB01563379_01, DOCOSAHEXAENOIC ACID (DHA) (C22:6 N3), Select-OB Plus DHAPrenatal Supplement Plus DHA, Vitafol-OB Plus DHAPrenatal Supplement Plus DHA, Q423345, DHA-[21,21,22,22,22-d5], SR-05000002130-1, SR-05000002130-4, BRD-K39965020-001-02-6, 4,7,10,13,16,19-Docosahexaenoic acid, (all cis)-, cis-4,7,10,13,16,19-Docosahexaenoic acid, >=98%, FA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)), z,z,z,z,z,z-docosa-4,7,10,13,16,19-hexaenoic acid, 800E8E72-BBF4-46F7-A60B-B8F2B54669C7, C22H32O2 (cis-4,7,10,13,16,19-docosahexaenoic acid), 4,7,10,13,16,19-Docosahexaenoic acid, (all-Z)- (8CI), cis-4,7,10,13,16,19-Docosahexaenoic acid, analytical standard, Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3), (4Z,7Z,10Z,13Z,16Z, 19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4, 7,10,13,16,19-hexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19- hexaenoic acid, 4,7,10,13,16,19-Docosahexaenoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)- (9CI), 1024594-51-1, cis-4,7,10,13,16,19-Docosahexaenoic acid, 500 mug/mL in ethanol, certified reference material
Drug Type	Small molecule
Formula	C₂₂H₃₂O₂
SMILES	CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)O
InChI	1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-
InChIKey	MBMBGCFOFBJSGT-KUBAVDMBSA-N
CAS Number	6217-54-5
ChEMBL ID	CHEMBL367149
ChEBI ID	CHEBI:28125
TTD ID	D0Q5XX
Drug Bank ID	DB03756
KEGG ID	C06429
Toxicity	Organism	Test Type	Route(Dose)
Structure			Download 2D MOL 3D MOL

Pair Name	Isoliquiritigenin, Docosahexaenoic acid
Partner Name	Isoliquiritigenin
Disease Info	[ICD-11: 2B91]	Colorectal cancer		Investigative
Biological Phenomena	Induction-->ROS generation
Gene Regulation	Up-regulation	Expression	CYCS	hsa54205
	Up-regulation	Expression	FAS	hsa355
	Up-regulation	Phosphorylation	MAPK8	hsa5599
In Vitro Model	HCT 116	Colon carcinoma	Homo sapiens (Human)	CVCL_0291
Result	Excessive ROS-induced JNK activation and cytochrome c release from mitochondria played a key role in the synergistic anticancer activity of CRC cells by cotreating with DHA and ISL.